Villus surface area (μm2) | Villus length (μm) | Villus diameter (μm) | Crypt depth (μm) | Villi/mm bowel | |
AR control, n=55 | 16 120 (585) | 312 (8) | 51 (1) | 56.9 (1.3) | 13.4 |
AR low dose rEpo (n=55) | 17 950 (725) | 354 (8)1-170 | 50 (2) | 61.8 (2.5) | 17.41-151 |
AR high dose rEpo (n=39) | 21 250 (722)1-170 | 401 (9)1-170 | 53 (1) | 54.9 (1.6) | 15.41-164 |
NP control (n=38) | 14 800 (1028) | 298 (14) | 52 (2) | 52.2 (1.3) | 15.4 |
NP rEpo treated dam (n=39) | 17 400 (716)1-150 | 361 (13)1-165 | 48 (2) | 49.8 (1.6) | 17.3 |
AR control, artificially raised pups; AR low dose rEpo, artificially raised pups, 200 U/kg/day enteral human recombinant erythropoietin (rEpo); AR high dose rEpo, artificially raised pups, 1000 U/kg/day enteral rEpo; NP control, nursing pups control; NP rEpo treated dam, nursing pups, dam treated with 200 U rEpo/day intraperitoneally.
↵1-150 p<0.05,
↵1-165 p<0.001 compared with pups nursing from rEpo treated dam;
↵1-151 p<0.05,
↵1-164 p<0.01,
↵1-170 p<0.0001 compared with artificially raised control pups.
Values are mean (SEM) or number.