Comparison of microsatellite analysis with MSH2 and /MLH1 immunohistochemical findings. Mismatch repair defective tumours are those carcinomas which showed loss of either MLH1 or MSH2 expression by immunohistochemistry
| MSI | |||
|---|---|---|---|
| MSS | MSI-H | Total | |
| MLH1 and MSH2 present | 274 | 6 | 280 |
| MLH1 loss | 1 | 24 | 28 |
| MSH2 loss | 0 | 3 | 3 |
| Total | 275 | 33 | 308 |
MSI, microsatellite instability; MSI-H, high level of microsatellite instability; MSS, microsatellite stable.