Table 1

Group data for meal stimulated gall bladder emptying


	Non-acromegalic control subjects (n=6)		Acromegalic patients Not treated with OT (n=6)		Treated with LTOT (n=8)		Patients with simple constipation (n=8)
	Placebo	Cisapride	Placebo	Cisapride	Placebo	Cisapride	Placebo	Cisapride
Fasting volume (ml)	21 (3.1)	36 (7.4)^1-c	33 (6.2)	41 (6.7)^1-c	39 (4.2)	63 (7.7)^1-a	19 (3.4)	33 (5.6)^1-b
Residual volume (ml)	4.7 (0.6)	9.7 (2.0)^1-c	9.4 (1.8)	12 (1.9)^1-c	27 (3.8)	43 (6.3)^1-a	7.0 (1.7)	10 (2.8)^1-c
Delta volume (ml)	16 (3.3)	26 (5.5)	24 (4.7)	29 (5.3)^1-c	12 (2.9)	20 (4.6)^1-c	12 (2.1)	22 (3.2)^1-b
Ejection fraction (%)	75 (5.0)	72 (2.7)	70 (4.1)	71 (3.2)	31 (5.8)	31 (5.3)	63 (4.9)	69 (3.7)
Rate of gall bladder emptying (ml/min)	0.47 (0.1)	0.79 (0.2)	0.59 (0.1)	0.66 (0.1)	0.24 (0.1)	0.48 (0.1)^1-c	0.30 (0.1)	0.56 (0.1)^1-b

Results are mean (SEM).
Unless otherwise indicated, differences between means were not statistically significant:
↵1-a p<0.001,
↵1-b p<0.01,
↵1-c p<0.05 versus placebo.
OT, octreotide; LTOT, long term octreotide.