Summary of patient data, diagnostic parameters, and immunoreactivity for LI-cadherin, villin, and sucrase-isomaltase in gastric biopsies
| Patients (n=30) | Histopathology | Immunofluorescence staining | |||||||
|---|---|---|---|---|---|---|---|---|---|
| No | Age (y) | Sex (M/F) | Gastroscopy diagnosis1-1 | H pylori status | Intestinal metaplasia1-2 | LI-cadherin1-3 | Sucrase- isomaltase1-4 | Villin1-4 | |
| 1 | 67 | F | GA,C | − | + | +++ | +++ | +++ | |
| 4 | 69 | F | GA | − | − | + | − | ++ | |
| 10 | 46 | F | GA | + | + | +++ | − | ++++ | |
| 13 | 78 | F | GA, VU | − | − | + | − | ++ | |
| 14 | 56 | M | — | − | − | ++ | ++ | +++ | |
| 15 | 69 | M | — | + | + | ++ | ++ | ++ | |
| 17 | 59 | M | GA | ? | + | +++ | +++ | +++ | |
| 18 | 59 | M | VU | ++ | + | ++ | − | ++ | |
| 24 | 90 | F | — | − | + | +++ | +++ | ++++ | |
| 27 | 47 | M | — | ? | + | +++ | +++ | +++ | |
↵1-1 —, no abnormality; GA, gastritis in the antrum; GC, gastritis in the corpus; VU, ventricular ulcer.
↵1-2 Intestinal metaplasia defined by conventional histological criteria: negative (−), positive (+), unknown (?).
↵1-3 Frequency of LI-cadherin positive cells in the biopsy: –, +, ++, +++, ++++.
↵1-4 Semiquantitative estimation of immunoreactivity for villin and sucrase-isomaltase in identical glands: –, +, ++, +++, ++++.