Table 2

Group data for mouth to caecum and large bowel transit times

Non-acromegalic control subjects (n=6) Acromegalic patients
Not treated with OT (n=6) 		Treated with LTOT (n=8) Patients with simple constipation (n=8)
Placebo Cisapride Placebo Cisapride Placebo Cisapride Placebo Cisapride
MCTT (min)120 (13)70 (7.4)2-b 163 (9.8)98 (11)2-c 268 (15)188 (16)2-a 135 (13)83 (8.5)2-a
LBTT (h) 27 (2.9)12 (2.9)2-b  51 (5.8)34 (7.2)2-c  53 (3.4) 29 (3.4)2-a  64 (2.4)45 (6.9)2-c

  • Results are mean (SEM).

  • Unless otherwise indicated, differences between means were not statistically significant:

  • ↵2-a p<0.001,

  • ↵2-b p<0.01,

  • ↵2-c p<0.05 versus placebo.

  • OT, octreotide; LTOT, long term octreotide; MCTT, mouth to caecum transit time; LBTT, large bowel transit time.