Table 2

A summary of the definitions of complications associated with pancreatic leakage in the double blind, multicentre, placebo controlled trials with octreotide

	Definition of leakage related complications
CT, computed tomography.
Trial	Pancreatic fistula	Abdominal abscess	Intra-abdominal fluid collection
Büchler et al 1992²⁶	Concentration of amylase and lipase in the drainage fluid g3 days postoperatively of g3 times the normal serum value and a drainage volume of g10 ml/24 hours	Collection of pus or infected fluid confirmed by ultrasound or CT guided aspiration and culture, or second laparotomy	Fluid collection (sterile) of at least 5X5 cm in diameter by ultrasound or CT
Pederzoli et al 1994¹	Drain output with amylase content g3 times the maximum normal value exceeding 10 ml/24 hours for ±4 days from day 4 after the operation	Collection of pus or infected fluid confirmed by ultrasound or CT guided aspiration and culture, or second laparotomy	Fluid collection (sterile) of at least 5x5 cm in diameter by ultrasound or CT
Montorsi et al 1995²⁷	Concentration of amylase and lipase in the drainage fluid g3 days postoperatively of g3 times the normal serum value and a drainage volume of g10 ml/24 hours	Collection of infected fluid with normal amylase concentration, with or without pus, confirmed by ultrasound or CT guided aspiration and culture, or second laparotomy	An intraperitoneal sac containing sterile fluid, with or without amylase
Friess et al 1995²⁸	Complications were defined and recorded as previously reported^1,^29,^35,³⁶