Table 2

Symptoms and signs at presentation in the 12 patients

	Patient No
	1	2	3	4	5	6	7	8	9	10	11	12
Lethargy		+			+		+	+	+	+		+
Malaise	+	+					+
Abdominal pain	+						+		+
Nausea		+	+					+		+
Vomiting			+					+		+
Diarrhoea		+
Pruritus							+
Anorexia			+				+	+				+
Weight loss							+
Rigors							+
Epistaxes							+	+
Miscarriages						+	+
Arthralgia			+
Jaundice		+	+	+			+	+	+	+
Ascites									+	+	+
Peripheral oedema												+
Encephalopathy		+		+						+		+
Haematemesis										+		+
Fever												+
Hepatomegaly	+	+		+			+
Splenomegaly	+		+	+		+		+	+		+
Anaemia			+	+					+			+