Transmucosal flux of 51Cr-EDTA in ileal mucosa in Ussing chambers
| Colon cancer (n=8) | CD non-inflamed (n=5) | CD inflamed (n=4) | |
|---|---|---|---|
| Data are given for the period of exposure to vehicle or sodium caprate (C10) as median (25–75th interquartile range) of transmucosal flux of 51Cr-EDTA (pmol/cm2/h). | |||
| *Increased permeability compared with ileal mucosa from patients with colon cancer (Mann-Whitney, p<0.05). | |||
| Vehicle experiments | 3.5 (1.0–5.0) | 5.8 (2.7–7.7) | 10 (6.0–17)* |
| C10 experiments | 15 (9.8–28) | 40 (36–48)* | 9.0 (3.0–15) |