Mucosal thiol methyltransferase (TMT), rhodanese (RHOD), and thiopurine methyltransferase (TPMT) activity at each site throughout the gastrointestinal tract
| TMT activity (pmol/mg/min) | RHOD activity (nmol/mg/min) | TPMT activity (pmol/mg/min) | |
|---|---|---|---|
| Oesophagus | 17.6 (5.4) (n=6) | 46.7 (18.1) (n=6) | 66.8 (12.2) (n=6) |
| Stomach | 51.5 (11.9) (n=9) | 127.6 (26.1) (n=9) | 189.2 (37.9) (n=9) |
| Small intestine | 91.7 (16.7) (n=9) | 157.6 (26.0) (n=9) | 156.4 (35.8) (n=9) |
| Right colon | 114.4 (15.9) (n=8) | 292.4 (80.9) (n=6) | 182.5 (34.2) (n=8) |
| Left colon | 82.4 (16.8) (n=11) | 245.6 (38.9) (n=10) | 209.5 (31.5) (n=11) |
| Rectum | 72.4 (10.7) (n=7) | 253.9 (39.4) (n=7) | 223.3 (21.1) (n=7) |
| Values are mean (SEM). | |||