Estimated percentage of young onset colorectal cancer (CRC) cases due to HNPCC in the study population
| Cancer site | SIR in study population | Penetrance in HNPCC4 (%) | Lifetime risk in general population32 (%) | RR in HNPCC | Estimate of % of young onset CRC cases due to HNPCC in study |
|---|---|---|---|---|---|
| HNPCC, hereditary non-polyposis colorectal cancer; SIR, standardised incidence ratio; RR, relative risk. | |||||
| Corpus uteri | 1.56 | 43 | 1.0 | 43 | 1.3 |
| Ovary | 2.56 | 9 | 1.32 | 6.82 | 26.8 |
| Stomach (men) | 1.07 | 19 | 1.27 | 15 | 0.5 |
| Stomach (women) | 0.76 | 19 | 0.38 | 50 | — |
| Bladder (men) | 0.95 | 10 | 1.47 | 6.8 | — |
| Bladder (women) | 0.91 | 10 | 0.42 | 23.8 | — |
| Kidney (men) | 1.30 | 18 | 0.72 | 25 | 1.25 |
| Kidney (women) | 1.10 | 18 | 0.33 | 54.5 | 1.89 |