Table 1

Clinicopathological features of 21 non-familial, non-ampullary small bowel adenocarcinomas

									Immunohistochemistry
	Sex	Age (y)	Site	Stage	Differentiation	Lymph nodes	Mucinous	Vascular invasion	hMLH1	hMSH2	β-Catenin	E-cadherin	p53
1	M	24	Duodenum	T3N1	Well	2 of 8	No	No	+	+	Reduced/cytoplasmic	+	+
2	F	49	Duodenum	T3Nx	Moderately	0	No	No	+	+	Reduced	+	+
3	M	83	Duodenum	Bx	Well	Bx	No	No	+	+	Reduced/nuclear	+	+
4	M	53	Jejunum	T3N1	Poor	2 of 7	No	Yes	+	+	Reduced/nuclear	+	+
5	M	72	Jejunum	T3Nx	Well	0	No	Yes	+	+	Reduced/nuclear	−	−
6	F	77	Ileum	T3N0	Moderately	0 of 3	No	No	+	+	Reduced/nuclear	−	−
7	M	76	Duodenum	Bx	Poor	Bx	Yes	Yes	+	+	Reduced	−	−
8	F	85	Duodenum	Bx	Well	Bx	No	No	+	+	Reduced/cytoplasmic	−	−
9	F	77	Jejunum	T4N1	Poor	2 of 4	No	Yes	+	+	Reduced/nuclear	−	−
10	F	54	Duodenum	Bx	Moderately	Bx	No	No	+	+	Reduced/nuclear	−	−
11	M	69	Duodenum	Bx	Poor	Bx	No	No	+	+	Reduced/nuclear	−	−
12	F	55	Jejunum	T3N0	Moderately	0 of 1	No	No	+	+	+	+	−
13	M	69	Jejunum	T3Nx	Moderately	0	No	Yes	+	+	Reduced/cytoplasmic	+	−
14	F	82	Ileum	T3Nx	Moderately	0	No	No	+	+	Reduced/nuclear	+	−
15	M	72	Ileum	T3Nx	Poor	0	No	Yes	+	+	+	+	+
16	M	58	Jejunum	T3Nx	Moderately	0	Yes	No	+	+	+	+	−
17	F	50	Duodenum	T2Nx	Well	0	No	Yes	+	+	+	+	−
18	F	70	Ileum	T3Nx	Poor	0	No	Yes	+	+	Reduced	−	−
19	M	53	Duodenum	Bx	Moderately	Bx	Yes	No	+	+	Reduced/nuclear	+	−
20	M	58	Ileum	T4Nx	Moderately	0	Yes	No	+	+	Reduced/nuclear	+	−
21	M	21	Duodenum	T4Nx	Moderately	0	No	No	+	+	Reduced/cytoplasmic	+	−