Relative risk (RR) of adenoma in the study group* compared with the reference group†
| No patients without adenoma | No patients with adenoma | Total | |||
|---|---|---|---|---|---|
| *Study group was less than 54 years or age at first adenoma was below 54 years; †reference group was less than 54 years of age. | |||||
| HNPCC, hereditary non-polyposis colorectal cancer; HCC, hereditary colorectal cancer; TCR, two close relatives with colorectal cancer. | |||||
| Reference group lifetime cancer risk 5% | |||||
| Women | 110 | 12 | 122 | ||
| Men | 191 | 25 | 216 | ||
| Total | 301 | 37 | 338 | ||
| Whole study group lifetime cancer risk 10–70% | |||||
| Women | 85 | 29 | 114 | RR 2.6 | |
| Men | 60 | 30 | 90 | RR 2.8 | |
| Total | 145 | 59 | 204 | RR 2.6 | p<0.001 |
| HNPCC gene carriers lifetime risk 70% | |||||
| Women | 12 | 9 | 21 | RR 4.4 | |
| Men | 8 | 10 | 18 | RR 4.8 | |
| Total | 20 | 19 | 39 | RR 4.5 | p<0.001 |
| HCC lifetime cancer risk 35% | |||||
| Women | 23 | 6 | 29 | RR 2.1 | |
| Men | 13 | 8 | 21 | RR 3.3 | |
| Total | 36 | 14 | 50 | RR 2.6 | p<0.001 |
| TCR lifetime cancer risk 15% | |||||
| Women | 15 | 11 | 26 | RR 4.3 | |
| Men | 10 | 2 | 12 | RR 1.4 | |
| Total | 25 | 13 | 38 | RR 3.1 | p<0.001 |