Comparison of cancer risks between different syndromes
| Cancer risk (risk/prevalence) | 95% CI | Cancer risk per adenoma | 95% CI | |
|---|---|---|---|---|
| *Statistically significant. | ||||
| 95% CI, 95% confidence interval. | ||||
| HNPCC, hereditary non-polyposis colorectal cancer; HCC, hereditary colorectal cancer; TCR, two close relatives with colorectal cancer. | ||||
| HNPCC, subjects at 70% risk* | 1.43 (70/49) | 1.09–2.06 | 1.19 (1.43/1.2) | 0.91–1.72 |
| HNPCC, subjects at 35% risk* | 1.84 (35/19) | 1.16–4.30 | 1.53 (1.84/1.2) | 0.97–3.59 |
| HNPCC, subjects at 17% risk | — | — | — | — |
| HNPCC, subjects at 5% risk | 0.38 (5/13) | — | 0.32 (0.38/1.2) | — |
| HCC, subjects at 70% risk | 1.40 (70/50) | — | 0.58 (1.4/2.4) | — |
| HCC, subjects at 35% risk* | 1.21 (35/29) | 0.92–1.75 | 0.50 (1.21/2.4) | 0.38–0.73 |
| HCC, subjects at 17% risk | 1.00 (17/17) | 0.55–8.75 | 0.42 (1.00/2.4) | 0.23–3.65 |
| TCR, subjects at 15% risk* | 0.45 (15/33) | 0.39–0.80 | 0.12 (0.45/3.8) | 0.10–0.21 |
| Normal population at 5% risk | 0.45 (5/11) | — | 0.23 (0.45/2.0) | — |