Mutations in or loss of heterozygosity (LOH) at TP53 by histological grade and size
| Mutation or LOH | |||
|---|---|---|---|
| + | − | p Value | |
| Fisher's exact test, mild plus moderate versus severe, <1 cm versus >1 cm. | |||
| Dysplasia | |||
| Mild | 1 | 20 | |
| Moderate | 5 | 25 | < 0.0008 |
| Severe | 10 | 9 | |
| Size | |||
| <1 cm | 4 | 21 | > 0.35 |
| >1 cm | 12 | 33 | |