Genotyping data of Finnish familial adenomatous polyposis kindreds with shared mutations, as well as six kindreds with mutations unknown (see text)
| Family ID | Mutated codon | D5S82 | D5S134 | D5S346 | D5S318 |
|---|---|---|---|---|---|
| The order of markers is D5S82-5 cM-D5S134-1 cM-D5S346 (APC)-1 cM-D5S318. | |||||
| The number of individuals genotyped is shown in parentheses after the family ID. | |||||
| For each marker, an allele shared by all affected members of a given family is shown. If only one member was studied, the individual alleles are shown separately (for example, F17, all markers). The same applies to families where affected members were heterozygous and shared both alleles (for example, F65, marker D5S82). The putative common disease haplotype in three kindreds harbouring a 4 bp deletion in codon 1059 is indicated in bold. | |||||
| F17 (1) | 216 | 3/3 | 5/7 | 7/7 | 2/3 |
| F30 (2) | 216 | 1 | 7 | 9 | 4 |
| F43 (1) | 283 | 2/5 | 7/7 | 2/9 | 2/2 |
| F51 (1) | 283 | 5/9 | 7/7 | 10/10 | 2/2 |
| F28 (1) | 876 | 5/8 | 7/7 | 2/8 | 1/2 |
| F32 (1) | 876 | 2/5 | 7/7 | 5/7 | 5/6 |
| F37 (3) | 1309 | 2 | 7 | 1 | 4 |
| F44 (1) | 1309 | 1/5 | 7/7 | 2/6 | 2/4 |
| F76 (1) | 1309 | 1/4 | 7/8 | 6/7 | 1/3 |
| F82 (1) | 1309 | 2/4 | 0/2 | 0/6 | 2/2 |
| F55 (1) | 1059 | 1/5 | 7/7 | 2/3 | 2/2 |
| F65 (2) | 1059 | 4/5 | 7 | 3 | 2/6 |
| F95 (2) | 1059 | 2/5 | 7 | 3/6 | 2 |
| F7 (2) | 1061 | ND | 7 | 9 | 1 |
| F61 (2) | 1061 | 5 | 7 | 7 | 2/3 |
| F2 (2) | Unknown | 4/5 | 7 | 1 | 5 |
| F5 (2) | Unknown | 1 | 6 | 8 | 1 |
| F31 (2) | Unknown | 1 | 7 | 2 | 2 |
| F57 (2) | Unknown | 1 | 7 | 1/6 | 2 |
| F70 (2) | Unknown | 4 | 7 | 7 | 6 |
| F85 (2) | Unknown | 2/5 | 7 | 4 | 2 |