Six biopsy specimens are assessed; each is graded on the scale of 0–4; the total score is achieved by adding the individual scores of the six biopsy specimens (maximum = 24). | |
Grade 0 | Normal |
Grade 1 | Mild oedema; inflammation in the lamina propria |
Grade 2 | Crypt abscess formation; inflammation in lamina propria |
Grade 3 | More severe inflammation with destructive crypt abscesses plus or minus granulomata |
Grade 4 | More severe inflammation with active ulceration |