Comparison of recipients who experienced graft fibrosis at a fast (greater than 0.8 fibrosis units per year) or slow (less than 0.8 units per year) rate
| Slow fibrosis (<0.8 units/year) | Fast fibrosis (>0.8 units/year) | Univariate analysis | Multivariate analysis | |
|---|---|---|---|---|
| HBsAg, hepatitis B virus surface antigen. | ||||
| *Serum status pre-transplant—all were serum HBsAg negative post-transplant. | ||||
| Data are median (range). | ||||
| n | 29 | 27 | ||
| Recipient age (y) | 50 (34–67) | 46 (28–65) | 0.3 | 0.7 |
| Recipient sex (M/F) | 24/5 | 21/6 | 0.6 | 0.8 |
| Caucasian | 15 | 14 | 0.4 | 0.5 |
| Cyclosporin/tacrolimus | 26/3 | 23/4 | 0.6 | 0.4 |
| Treated rejection | 10 | 11 | 0.6 | 0.12 |
| >1 episode rejection | 3 | 0 | 0.2 | 0.8 |
| HBsAg positive* | 3 | 2 | 0.7 | 0.5 |
| Cold ischaemic time (min) | 787 (261–1280) | 780 (353–1055) | 0.7 | 0.4 |
| Warm ischaemic time (min) | 44 (25–58) | 51 (33–76) | 0.02 | 0.01 |
| Donor sex (M/F) | 18/11 | 20/7 | 0.34 | 0.34 |
| Donor age (y) | 38 (15–64) | 45 (17–67) | 0.09 | 0.02 |
| Date of transplantation (pre/post 11/96) | 16/13 | 12/15 | 0.42 | 0.96 |