Histological parameters in patients with paired liver biopsies before (pre) and after (post) weight reduction
| α-SMA‡ (cells/mm2) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Waist* (cm) | BMI* (kg/m2) | Grade of steatosis | Stage of fibrosis† | Portal | Acinar | ||||||||||||
| Pt No | Sex | Age (y) | Viral genotype | % wt loss* | Time since antiviral therapy (months) | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post |
| *At the time of liver biopsy. | |||||||||||||||||
| †Modified Knodell score (fibrosis stage 0–6). | |||||||||||||||||
| ‡α smooth muscle actin immunoperoxidase. | |||||||||||||||||
| n/a, not applicable. | |||||||||||||||||
| 1 | M | 42 | 3 | 14.2 | n/a | 96 | 85 | 26 | 23 | 3 | 1 | 1 | 1 | 347 | 60 | 2 | 0 |
| 3 | M | 41 | 3 | 9.7 | n/a | 99 | 88 | 28 | 25 | 3 | 2 | 4 | 2 | 412 | 363 | 67 | 7 |
| 4 | F | 43 | 1 | 7.6 | 10 | 106 | 87 | 32 | 30 | 1 | 0 | 2 | 1 | 488 | 12 | 34 | 0 |
| 5 | M | 42 | 3 | 13.1 | n/a | 110 | 98 | 34 | 31 | 3 | 1 | 4 | 1 | 219 | 156 | 2 | 0 |
| 6 | F | 42 | 1 | 12.7 | 40 | 92 | 90 | 33 | 29 | 2 | 1 | 3 | 3 | 168 | 199 | 12 | 4 |
| 8 | M | 42 | 1 | 7.8 | 6 | 119 | 101 | 31 | 29 | 1 | 0 | 6 | 6 | 1273 | 691 | 81 | 36 |
| 11 | F | 49 | 2 | 6.9 | n/a | 90 | 85 | 27 | 26 | 3 | 2 | 3 | 1 | 410 | 123 | 30 | 31 |
| 14 | F | 29 | 3 | 3.9 | 36 | 74 | 70 | 21 | 20 | 2 | 1 | 3 | 1 | 319 | 239 | 40 | 36 |
| 15 | F | 43 | 3 | 2.4 | n/a | 104 | 101 | 40 | 39 | 3 | 3 | 1 | 3 | 209 | 141 | 8 | 2 |
| 19 | M | 33 | 1 | 2.6 | 6 | 102 | 97 | 29 | 28 | 1 | 0 | 3 | 3 | 225 | 49 | 56 | 0 |