Comparative affinities for cloned human σ1 receptor of JO 2871, its stereoisomer JO 2870, and the corresponding racemate JO 2514, with igmesine and pentazocine
| Compound | Ki (nM) | nH |
|---|---|---|
| Results are mean (SEM) of three separate determinations. | ||
| JO 2871 | 0.26 (0.10) | 1.34 (0.35) |
| JO 2870 | 6.7 (4.3) | 0.98 (0.24) |
| JO 2514 | 1.4 (0.8) | 1.3 (0.2) |
| Igmesine | 18 (3) | 1.03 (0.05) |
| (+)Pentazocine | 8.2 (1.2) | 0.84 (0.13) |