Table 1

Serum antiurease IgG and IgA responses by treatment group

	Serum antiurease IgG positive/total volunteers*	Serum antiurease IgG titre median† (range)	Serum antiurease IgA positive/total volunteers*	Serum antiurease IgA titre median† (range)
*Positive status defined as a fourfold increase from baseline. †Titres are expressed as fold change as compared with baseline. Positive results only. ‡One serum sample not available for analysis.
Group 1: Soluble urease, no LT	0/6	N/A	1/6	4.7
Group 2: Soluble urease, 0.1 μg LT	1/6	15.4	1/6	5.3
Group 3: Soluble urease, 0.5 μg LT	1/6	4.2	0/6	N/A
Group 4: Soluble urease, 2.5 μg LT‡	2/5	58 (6.5–109.8)	3/5	4.5 (4.1–28.3)
Group 5: Urease capsule, no LT	1/6	152	1/6	24.8
Group 6: Urease capsule, 0.1 μg LT	1/6	7.3	1/6	9.9
Group 7: Urease capsule, 2.5 μg LT	1/6	15.3	2/6	4.3 (4.2–4.4)