Distribution of risk factors in case subjects with Barrett’s oesophagus, oesophageal adenocarcinoma, and oesophagogastric junctional adenocarcinoma, and in the control group with gastro-oesophageal reflux disease symptoms
| Cases (n=58) | Controls (n=106) | OR* | p Value† | |
|---|---|---|---|---|
| *Crude odds ratio computed without taking any other risk factors into account. | ||||
| †From Pearson’s χ2 test. | ||||
| Alcohol consumption per week | ||||
| <1 drink | 28 (53%) | 63 (68%) | 0.097 | |
| 1–5 | 9 (18%) | 19 (20%) | 1.07 | |
| 6–10 | 8 (16%) | 8 (9%) | 2.25 | |
| >10 | 6 (12%) | 3 (3%) | 4.5 | |
| Smoker (current or former) | 41 (71%) | 53 (52%) | 2.18 | 0.0374 |
| Coffee consumption | 42 (72%) | 77 (73%) | 0.99 | 0.8794 |
| Obesity | ||||
| Current | 20 (35%) | 48 (45%) | 0.63 | 0.2394 |
| 1 y ago | 30 (52%) | 54 (51%) | 1.03 | 0.946 |
| 5 y ago | 29 (50%) | 47 (44%) | 1.25 | 0.5953 |
| 10 y ago | 27 (47%) | 29 (27%) | 2.31 | 0.0211 |
| 20 y ago | 21 (36%) | 16 (15%) | 3.16 | 0.0042 |
| Family history of BO or OAC/OGJAC | 14 (24%) | 5 (5%) | 6.43 | 0.0005 |