Clinical features of cirrhotics with “clinically significant” hepatopulmonary syndrome (HPS), “subclinical” HPS, and no HPS
| “Clinically significant” HPS* (n=14) and positive contrast echo | “Subclinical” HPS† (n=13) and positive contrast echo | No HPS (n=71) | p Value | |
|---|---|---|---|---|
| *Defined as hypoxaemia (PaO2 <70 mm Hg). | ||||
| †Defined as normoxaemia (PaO2 ≥70 mm Hg and AaDO2 >age related threshold). | ||||
| Dyspnoea | 8 (57%) | 1 (8%) | 4 (6%) | <0.001 |
| Spider naevi | 11 (79%) | 7 (54%) | 28 (39%) | <0.05 |
| Palmar erythema | 8 (57%) | 4 (31%) | 35 (49%) | NS |
| Child-Score | 11.6 (1.9) | 10.5 (3.1) | 9 (2.5) | <0.05 |
| OLT | 2 (14%) | 5 (38%) | 12 (17%) | |
| Complications | 0 | Embolic brain infarct 2; wound infection 1; prolonged weaning 1 | 0 | |
| Outcome | Both died, 2 and 10 months after OLT | 1 died, 6.5 months after OLT | 2 died, 7.5 and 9 months after OLT | |