Relationship between the presence of gastric lesions and mutation of the APC gene in patients with familial adenomatous polyposis
| Fundic gland polyposis | Gastric adenoma | |||||
|---|---|---|---|---|---|---|
| Positive (n=16) | Negative (n=15) | p Value | Positive (n=12) | Negative (n=19) | p Value | |
| *Mann-Whitney U test. | ||||||
| †Fisher’s exact probability test. | ||||||
| ‡Data not available in one patient. | ||||||
| Age (y) | 33.4 (14.4) | 46.5 (16.4) | <0.05* | 41.8 (3.4) | 38.5 (18.4) | 0.43* |
| Sex (M/F) | 8/8 | 11/4 | 0.17† | 6/6 | 13/6 | 0.26† |
| APC gene mutation | ||||||
| Positive (proximal/distal) | 12 (4/8) | 10 (2/8)‡ | 0.57† | 12 (2/10) | 10 (4/6)‡ | <0.01† |
| Negative | 4 | 4‡ | 0 | 8‡ | ||