Table 3

Distribution of DRB1 phenotypes in hepatitis C virus (HCV) chronically infected patients with normal or elevated alanine aminotransferase (ALT) levels

DRB1*Normal ALT (n=83) (%)Elevated ALT (n=233) (%)p Value† (pc)Odds ratio (95% CI)
†Only significant p values are indicated.
‡DR2 subtyping (DR15, DR16) was not available for 14 individuals.
01 5 (6%)45 (19%) 0.004 (0.07)0.26 (0.10 to 0.70)
0312 (14%)44 (19%)
0422 (27%)56 (24%)
0719 (23%)66 (28%)
0810 (12%)11 (5%) 0.02 (0.58)2.76 (1.12 to 6.77)
09 2 (2%) 2 (1%)
10 1 (1%) 6 (3%)
1136 (43%)57 (24%)<0.001 (0.03)2.36 (1.39 to 4.00)
12 2 (2%) 2 (1%)
1319 (23%)64 (27%)
1410 (12%)17 (7%)
1510 (12%)41 (18%)
16 7 (8%)12 (5%)
02‡ 1 (1%)13 (6%)