Effect of appendicectomy on Crohn’s disease characteristics (n=335)
| Appendicectomy | |||||
|---|---|---|---|---|---|
| Phenotype | n | Yes (n=36) | No (n=299) | OR (95% CI) | p Value |
| *t test was used for means. | |||||
| †3 cases of pure perianal disease omitted from analysis in view of small numbers. | |||||
| ‡1 case of pure perianal disease was not included in analysis. | |||||
| Mean (SEM) age at diagnosis (y) | 35.6 (2.0) | 29.6 (0.9) | 0.02* | ||
| Immunosuppression | |||||
| No | 191 | 22 (61.1%) | 169 (56.5%) | ||
| Yes | 144 | 14 (38.9%) | 130 (43.5%) | 0.83 (0.41–1.68) | 0.60 |
| Bowel resection | |||||
| No | 135 | 13 (36.1%) | 122 (40.8%) | ||
| Yes | 200 | 23 (63.9%) | 177 (59.2%) | 1.22 (0.59–2.50) | 0.59 |
| Distribution | |||||
| Ileocolonic | 128 | 8 (22.2%) | 120 (40.1%) | 1.9 (referent) | |
| Ileal | 123 | 18 (50%) | 105 (35.1%) | 2.4 (1.0–5.9) | 0.14 |
| Colonic | 81 | 9 (25.0%) | 72 (24.1%) | 1.9 (0.70–5.2) | |
| Perianal† | 3 | 1 (2.8%) | 2 (0.7%) | — | |
| Duration between appendicectomy and CD (y)‡ | |||||
| Ileal (mean (SEM)) | 18 | 15.0 (2.8) | — | ||
| Colonic (mean (SEM)) | 9 | 16.6 (4.4) | — | 0.94 | |
| Ileocolonic (mean (SEM)) | 8 | 16.3 (2.7) | — | ||
| Age at appendicectomy among CD patients (y)‡ | |||||
| Ileal (mean (SEM)) | 18 | 19.4 (2.4) | |||
| Colonic (mean (SEM)) | 9 | 23.2 (3.4) | |||
| Ileocolonic (mean (SEM)) | 8 | 16.5 (1.6) | 0.28 | ||