Comparison of cyclooxygenase 2 (COX-2) staining between adenocarcinomas of the gastric cardia (present study) and adenocarcinomas of the distal oesophagus developed in a Barrett segment (Buskens and colleagues12)
| COX-2 expression | Tumour localisation | ||
|---|---|---|---|
| Cardia (n = 134) (n (%)) | Oesophagus (n = 145) (n (%)) | p Value | |
| In cardia carcinomas, significantly less (intense) COX-2 staining was found (p = 0.0001). | |||
| 0 (24) | 22 (16.4) | 2 (1.4) | 0.0001 |
| 1 (85) | 57 (42.5) | 28 (19.3) | |
| 2 (155) | 53 (39.6) | 102 (70.3) | |
| 3 (15) | 2 (1.5) | 13 (9.0) | |