Table 1

Tests of visceral hypersensitivity and main pitfalls

MethodSummary of predominant pitfalls/unclear significance
ThresholdsUnclear significance relative to patient symptoms and prediction of responsiveness to therapy; assesses initial and pain thresholds rather than broad range of sensation
Sensation of phasic distensionUnclear significance relative to patient symptoms and prediction of responsiveness to therapy; fewer centres use this method; assesses range of sensations
Brain imagingExpensive, questionably applicable to practice; signal to noise ratio; complicated analyses; blood flow changes in sensory centres influenced by vigilance, unpleasantness, intensity of stimulus, and possibly sex