Final logistic regression model for anti-Hp IgG seropositive/borderline participants and for duodenal ulcer disease. Eleven year cumulated incidence of peptic ulcer disease (PUD). Odds ratios and 95% confidence intervals (CI)*
| Baseline exposure (reference category)‡ | Anti-Hp IgG positive or borderline participants | Duodenal ulcer† | ||||||
|---|---|---|---|---|---|---|---|---|
| PUD incidence | Multivariate adjusted* | PUD incidence | Multivariate adjusted* | |||||
| % | n | Odds ratio | 95% CI | % | n | Odds ratio | 95% CI | |
| *All odds ratios are mutually adjusted and adjusted for age, sex, and psychosocial factors. | ||||||||
| †All duodenal ulcer patients were former or current smokers. | ||||||||
| ‡Blank cells indicate that the variable was inapplicable. | ||||||||
| Anti-Hp IgG sero-status | ||||||||
| (Seronegative) | 0.4 | 1400 | 1.0 | — | ||||
| Borderline | 2.7 | 442 | 6.0 | 1.7;20.1 | ||||
| Seropositive | 4.0 | 544 | 16.0 | 5.2;49.3 | ||||
| Cumulative tobacco consumption† | ||||||||
| (Never-smoker) | 1.1 | 270 | 1.0 | — | ||||
| Former smoker | 3.1 | 225 | 4.0 | 0.8;20.8 | ||||
| 1–14.99 g/day | 9.6 | 239 | 12.7 | 2.8;56.8 | ||||
| 15–24.99 g/day | 7.9 | 215 | 8.5 | 0.4;25.1 | ||||
| ≥25 g/day | 3.6 | 55 | 3.2 | 0.8;11.9 | ||||
| Cumulative number of cigarettes smoked daily | ||||||||
| 0 | 2.7 | 403 | 1.0 | — | 0.6 | 975 | 1.0 | — |
| 1–9 cigarettes | 5.4 | 168 | 2.4 | 0.9;6.4 | 1.4 | 368 | 2.6 | 0.7;9.2 |
| 10–14 cigarettes | 6.8 | 148 | 2.3 | 0.9;6.4 | 2.2 | 364 | 3.6 | 1.1;12.1 |
| 15–20 cigarettes | 7.6 | 224 | 2.9 | 1.2;6.8 | 2.9 | 548 | 5.0 | 1.8;14.4 |
| ≥21 cigarettes | 8.2 | 61 | 2.5 | 0.7;9.0 | 3.8 | 131 | 7.7 | 2.0;29.0 |
| Wine (weekly consumption) | ||||||||
| (Never drink wine) | 7.2 | 335 | 1.0 | — | 2.5 | 676 | 1.0 | — |
| 1–3 glasses of wine | 3.6 | 440 | 0.5 | 0.2;1.2 | 1.4 | 1099 | 0.5 | 0.2;1.2 |
| ≥4 glasses of wine | 5.2 | 229 | 0.6 | 0.3;1.5 | 1.3 | 611 | 0.4 | 0.1;1.2 |
| Spirits (weekly consumption) | ||||||||
| (Never drink spirits) | 4.8 | 547 | 1.0 | — | 1.5 | 1251 | 1.0 | — |
| 1–2 glasses of spirits | 5.1 | 311 | 2.4 | 1.1;5.4 | 1.6 | 770 | 1.7 | 0.8;4.0 |
| ≥3 glasses of spirits | 6.8 | 146 | 1.8 | 0.7;4.4 | 2.5 | 365 | 1.7 | 0.7;4.6 |
| Leisure time energy expenditure | ||||||||
| (Sedentary) | 8.8 | 239 | 1.0 | — | 2.4 | 574 | 1.0 | — |
| Ambulatory | 4.0 | 524 | 0.3 | 0.2;0.7 | 1.4 | 1273 | 0.8 | 0.4;1.8 |
| Active | 4.1 | 241 | 0.6 | 0.2;1.4 | 1.5 | 539 | 1.2 | 0.4;3.2 |
| Uspecified gastrointestinal drugs at study entry | ||||||||
| (Never-infrequent use) | 4.4 | 856 | 1.0 | — | 1.4 | 2037 | 1.0 | — |
| Previous use | 4.5 | 44 | 1.3 | 0.3;6.0 | 0.8 | 123 | 0.5 | 0.1;4.2 |
| Current use | 11.7 | 103 | 3.0 | 1.4;6.5 | 4.5 | 224 | 3.4 | 1.5;7.4 |
| Minor tranquilliser use at study entry in 1982 | ||||||||
| (Never-infrequent use) | 3.9 | 924 | 1.0 | — | 1.4 | 2212 | 1.0 | — |
| Previous use | 5.9 | 17 | 2.9 | 0.3;24.9 | 0.0 | 27 | 0.1 | — |
| current use | 12.7 | 55 | 2.8 | 1.1;7.3 | 4.5 | 107 | 2.6 | 0.8;7.5 |