Quantitative bacteriology of caecal content by bacterial cultures
| Treatment | Direct microscopic bacterial counts (×108) | Total aerobes (×107) | E coli (×107) | Enterococci (×107) | Total anaerobes (×108) | Bacteroides spp (×107) |
|---|---|---|---|---|---|---|
| Direct microscopic bacterial counts and caecal concentrations of aerobic bacteria, Escherichia coli, enterococci, as well as total anaerobic bacteria, including Bacteroides spp, in gnotobiotic IL-10−/− mice colonised with specific pathogen free flora and treated with ciprofloxacin (Cipro), metronidazole (MNZ), or vancomycin-imipenem (V+I). Values are given as mean (SEM) colony forming units (CFU) per gram caecal contents. | ||||||
| *p<0.05, **p<0.01 versus water controls. | ||||||
| Water | 38 (12) | 5 (2) | 7 (3) | 48 (20) | 86 (30) | 32 (8) |
| MNZ | 43 (7) | 20 (10) | 84 (13)** | 57 (30) | 4.8 (5)* | <0.001** |
| Cipro | 24 (6) | <0.001** | <0.001** | 0.2 (0.1)** | 96 (50) | 28 (5) |
| V+I | 1 (0.1)** | 21 (10) | <0.001** | <0.001** | <0.001** | <0.001** |