Comparison of the use of calcium channel blockers between patients with colonic diverticular perforation and two hospital based control groups
| Drug | Patients with PCDD (n = 120) (% use) | Ophthalmology controls (n = 240) | Dermatology controls (n = 240) | ||
|---|---|---|---|---|---|
| % use | OR (95% CI)* | % use | OR (95% CI)* | ||
| PCDD, perforated colonic diverticular disease. | |||||
| *Odds ratio (OR) (with 95% confidence interval (CI)) of developing PCDD if taking a drug compared with not taking a drug. | |||||
| All calcium channel blockers | 6.7 | 14.2 | 0.4 (0.2–0.9) | 15.8 | 0.4 (0.2–0.8) |
| Modified release preparations | 2.5 | 8.3 | 0.3 (0.1–0.9) | 11.7 | 0.2 (0.1–0.6) |
| Short acting preparations | 4.2 | 5.9 | 0.7 (0.2–2.0) | 4.6 | 0.9 (0.3–2.7) |