Primary analysis: complete healing after eight weeks of treatment in the glyceryl trinitrate (GTN) and placebo groups
| Treatment group | Proportion healed (%) | 95% CI |
|---|---|---|
| *χ2 test for trend, glyceryl trinitrate (GTN) versus placebo (χ2=0.7, p=0.3). | ||
| †χ2 test for trend, GTN versus placebo (χ2=1.4, p=0.1). | ||
| Intention to treat analysis* | ||
| Placebo | 18/48 (37.5%) | 0.24–0.53 |
| 0.1% GTN | 23/49 (46.9%) | 0.33–0.63 |
| 0.2% GTN | 19/47 (40.4%) | 0.26–0.56 |
| 0.4% GTN | 20/37 (54.1%) | 0.37–071 |
| Per protocol analysis† | ||
| Placebo | 14/41 (34.1%) | 0.20–0.51 |
| 0.1% GTN | 23/45 (51.1%) | 0.36–0.66 |
| 0.2% GTN | 14/37 (37.8%) | 0.22–0.56 |
| 0.4% GTN | 18/32 (56.3%) | 0.38–074 |