Neurochemical code of colonic myenteric neurones in control tissues and tissues from non-inflamed and inflamed areas in ulcerative colitis
| Control | Non-inflamed | Inflamed | |
|---|---|---|---|
| Values are mean (SEM). | |||
| *p<0.05, **p<0.01 compared with controls. | |||
| ChAT, choline acetyltransferase; SP, substance P; VIP, vasoactive intestinal peptide. | |||
| ChAT/− | 26.9 (2.7) | 15.8 (2.8)** | 18.8 (2.4)* |
| ChAT/SP/− | 5.0 (0.5) | 13.9 (1.7)** | 11.8 (1.4)** |
| ChAT/VIP/− | 2.6 (0.7) | 3.7 (2.1) | 2.4 (0.7) |
| ChAT/VIP/SP/− | 0.4 (0.1) | 1.4 (0.7) | 0.7 (0.2) |
| VIP/SP/− | 0.0 (0.0) | 0.2 (0.1) | 0.1 (0.1) |
| VIP/− | 4.0 (1.0) | 4.5 (1.9) | 6.2 (2.7) |
| SP/− | 0.6 (0.2) | 5.0 (1.7) | 3.1 (0.7)* |