Total | 82 | 100 | 280 | 100 | |
Median time from diagnosis to chemotherapy (days) | 26 | | 52 | | |
Sex |
Male | 60 | 73 | 169 | 60 | |
Female | 22 | 27 | 111 | 40 | 0.03 |
Age (y) |
Median (range) | 59 (19–80) | | 62 (30–82) | | |
PS at commencement of chemotherapy |
0–1 | 51 | 62 | 225 | 80 | |
⩾2 | 31 | 38 | 55 | 20 | 0.001 |
Site of primary tumour |
Right sided | 13 | 16 | 69 | 25 | |
Residual colon | 31 | 38 | 119 | 43 | |
Rectum | 38 | 46 | 92 | 33 | 0.06 |
Sites of metastases |
Peritoneal/omental | 11 | 13 | 56 | 20 | |
Non-peritoneal/omental | 71 | 87 | 224 | 80 | 0.18 |
Biochemical parameters |
Mean serum alk phosph (U/l) | 329 | | 179 | | <0.001 |
Mean serum albumin (g/l) | 34.5 | | 38.7 | | <0.001 |
Mean CEA (μg/l) | 3139 | | 809 | | 0.006 |