Author | Year | Region | Country | No of patients | No of probands | No of call-up cases | % Isolated cases | % CRC in probands | % CRC in call-up cases | Incidence rate ×10−6 | Prevalence rate ×10−5 | % FAP with CRC/all CRC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FAP, familial adenomatous polyposis; CRC, colorectal cancer. | ||||||||||||
Bussey1 | 1975 | London | UK | 410 | 293 | 117 | 45 | 66 | 9 | |||
Vasen19 | 1990 | — | Holland | 230 | 104 | 126 | 46 | 47 | 4 | |||
Penna28 | 1992 | Paris | France | 141 | 45 | 3 | ||||||
Goh37 | 1992 | — | Singapore | 58 | 89 | 13 | ||||||
Morton29 | 1993 | West Midland | UK | 107 | 64 | 6 | ||||||
Bertario7 | 1994 | — | Italy | 604 | 441 | 163 | 48 | 10 | ||||
Järvinen22 | 1994 | — | Finland | 192 | 116 | 76 | 66 | 7 | 1.58 | 2.63 | 0.14 | |
Ponz de Leon30 | 1999 | Modena | Italy | 156 | 41 | |||||||
Björk17 | 2000 | — | Sweden | 431 | 216 | 215 | 67 | 3 | 0.90 | 3.16 | 0.023 | |
Heiskanen18 | 2000 | — | Finland | 236 | 116 | 120 | 61 | 4 | ||||
Present study | — | Denmark | 434 | 252 | 182 | 35 | 68 | 3 | 1.90 | 3.19 | 0.07 |