Distribution of aquaporin (AQP) water channels and cystic fibrosis transmembrane conductance regulator (CFTR) in human pancreas
| Acinar cells | Intercalated ducts | Intralobular ducts | Small interlobular ducts | Large interlobular ducts | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AP | BL | Centroacinar cells | AP | BL | AP | BL | AP | BL | AP | BL | |
| AP, apical (luminal) membrane; BL, basolateral membrane. | |||||||||||
| CFTR | ++ | − | ? | ++ | − | + | − | − | − | − | − |
| AQP1 | − | − | ++ | ++ | ++ | ++ | + | + | − | − | − |
| AQP5 | − | − | − | ++ | − | ++ | − | − | − | − | − |
| AQP8 | ++ | − | − | − | − | − | − | − | − | − | − |