Patient characteristics
| Patient No | Age/sex | Diagnosis | Duration of IBD (y) | Previous surgery | Prednisolone dose (mg)/duration (days) | CDAI | EIM | Localisation | CDAI after 3 applications | Duration of remission/clinical course/follow up (months) |
|---|---|---|---|---|---|---|---|---|---|---|
| CD, Crohn’s disease; IC, indeterminate colitis; J, jejunum; I, ileum; C, colon; R, rectum; EIM, extraintestinal manifestation; PG, pyoderma gangrenosum; EN, erythema nodosum; PSC, primary sclerosing cholangitis. | ||||||||||
| *Second course of cyclophosphamide application after flare up (see patients and methods). | ||||||||||
| —, Data not available. | ||||||||||
| 1 | 23/F | CD | 10 | None | 60 iv/12 | 294 | PG | I, C, R | 111 | 29/relapse, then second course |
| 2 | 22/F | CD | 1 | None | 80 po/21 | — | EN, arthritis | I, C | 102 | 35/remission/37 |
| 3 | 29/M | IC | 16 | Explorative laparotomy and doubleloop ileostomy | 50 po/21 | 292 | PSC | I, C, R | 54 | 20/proctocolectomy due to an adenoma/38 |
| 4 | 20/F | CD | 3 | None | 100 iv/18 | 290 | PSC | Stomach, C | 72 | 18/relapse (steroid treatment)/39 |
| 5 | 19/M | CD | 2 | Explorative laparotomy | 60/50 | 303 | None | J, I, C | 96 | 25/25 |
| 6 | 30/F | CD | 19 | Subtotal colectomy 1984, ileorectostomy 1987, 2 anastomosis resections 1988, 1997 | 60 po/19 | 479 | Arthritis | I, C | 189 | Clinical improvement but not remission |
| 7 | 29/F | CD | 9 | Sigmoid colon resection 1997, fistulae and abscess drainage 1997, 1999, 2000 | 80 iv/7 | 264 | EN, arthritis | I, C, R | 0 | 6/relapse after a 5 month remission period (hemicolectomy)/12 |
| 1* | 25/F | CD | 12 | None | 100 iv/21 | 316 | None | C, R | 69 | 12/remission/12 |