Comparison of femur dimensions, composition, and tibial bone mineral density in rats at termination at 16 weeks
| SC (n=10) | PPVL (n=9) | PSS (n=10) | p Value SC v PPVL | p Value SC v PSS | |
|---|---|---|---|---|---|
| SC, sham operated surgical controls; PPVL, partial portal vein ligation; PSS, portasystemic shunting; BMD, bone mineral density; BMC, bone mineral content. | |||||
| Femur length (mm) | 30.47 (2.36) | 30.78 (1.94) | 27.83 (1.25) | 0.86 | 0.008 |
| Mid shaft thickness (mm) | 4.13 (0.46) | 3.98 (0.31) | 3.63 (0.30) | 0.44 | 0.017 |
| Femur mass (g) | 0.416 (0.09) | 0.385 (0.06) | 0.295 (0.03) | 0.37 | <0.001 |
| mg Ca2+/femur | 70.92 (14.52) | 66.29 (14.62) | 50.69 (5.40) | 0.50 | 0.003 |
| Femur mass/100 g body mass | 0.108 (0.009) | 0.100 (0.02) | 0.137 (0.03) | 0.08 | 0.01 |
| mg Ca2+/mm bone | 2.31 (0.30) | 2.18 (0.36) | 1.82 (0.13) | 0.40 | 0.002 |
| mg Ca2+/mg bone | 0.164 (0.03) | 0.172 (0.02) | 0.172 (0.003) | 0.21 | 0.34 |
| Tibial BMD (g/cm2) | 0.223 (0.005) | 0.218 (0.009) | 0.199 (0.01) | 0.12 | <0.001 |
| Tibial BMC (g) | 0.244 (0.05) | 0.253 (0.05) | 0.184 (0.02) | 1.00 | 0.004 |