Table 3

Logistic regression analysis of potential risk factors for gastro-oesophageal reflux disease in the study population

VariableOdds ratio (95% CI)p Value
*Excess alcohol intake was defined as >28 units per week for a man and >21 units per week for a woman.
HRT, hormone replacement therapy; GI, gastrointestinal.
Age (per y)1.03 (1.02–1.03)<0.001
Anticholinergic drug therapy1.52 (1.12–2.05)0.006
Body mass index (per unit increase)1.11 (1.09–1.13)<0.001
Ever smoked1.31 (1.10–1.54)0.001
Excess alcohol*0.99 (0.99–1.00)0.67
Sex0.91 (0.68–1.22)0.52
Oral contraceptive or HRT0.76 (0.63–0.93)0.006
Parental family history of upper GI disease1.46 (1.22–1.74)<0.001
Right handed1.06 (0.82–1.36)0.66