Differentially expressed genes in adenomatous (low grade dysplasia, D1) versus normal colonic samples (differentially regulated in at least 3/6 patients)
| Gene (accession No) | Upregulated (fold increase) | Downregulated (fold decrease) | Regulation |
|---|---|---|---|
| Values represent the mean up- or downregulation of all experiments in each patient. | |||
| *4 (6) indicates 4 of 6 patients regulated differentially. | |||
| M, median; MAPK p38, mitogen activated protein kinase p38; IFGR, interferon γ receptor; TSP2, thrombospondin 2; FAST kinase, Fas activated serine/threonine kinase. | |||
| p21-rac1; ras related protein TC25 (M29870, M31467) | 2.4 | ↑ 4 (6)* | |
| 3.4 | |||
| 3.0 | |||
| 4.5 | |||
| (M=3.3) | |||
| MAPK p38 (L35253, L35263) | 2.8 | ↑ 3 (6) | |
| 3.3 | |||
| 3.5 | |||
| (M=3.2) | |||
| IFGR (A09781) | 3.7 | ↑ 3 (6) | |
| 4.0 | |||
| 2.8 | |||
| (M=3.5) | |||
| TSP2 (L12350) | 8.3 | ↓ 3 (6) | |
| 8.7 | |||
| 9.8 | |||
| (M=8.9) | |||
| p53 cellular tumour antigen (M14694, M14695) | 2.5 | ↓ 3 (6) | |
| 3.2 | |||
| 28.2 | |||
| (M=11.3) | |||
| FAST kinase (X86779) | 4.6 | ↓ 3 (6) | |
| 9.9 | |||
| 2.5 | |||
| (M=5.7) | |||