Patient demographics
| PI | PS→PI | PS | p Value* | |
|---|---|---|---|---|
| Values are mean (SD). | ||||
| PI, pancreatic insufficiency; PS, pancreatic sufficiency. | ||||
| *Comparison between PS and PI cohorts by Student’s t test | ||||
| Sex (M/F) | 348/262 | 14/8 | 60/50 | 0.7 |
| Age at diagnosis (y) | 2.3 (4.9) | 3.1 (6.5) | 9.8 (9.5) | 0.001 |
| Sweat chloride (mmol/l) | 103 (14) | 99 (18) | 87 (21) | 0.001 |
| Age at assessment (y) | 21.0 (10.4) | 22.6 (8.4) | 27.3 (11.7) | 0.03 |
| FEV1 (% predicted) | 62.0 (29.4) | 65.7 (25.9) | 76.2 (28.7) | 0.001 |
| Weight (% ideal for height) | 99.8 (14.6) | 99.9 (16.3) | 108.8 (18.3) | 0.001 |
| Mortality (%) | 16.6 | 9.1 | 4.6 | 0.001 |