Ductular function | Acinar function | ||||||
---|---|---|---|---|---|---|---|
Functional class | n | Fluid† (ml/kg/h) | Bicarbonate‡ (mmol/kg/h) | Chloride‡ (mmol/kg/h) | Trypsin* (U/kg/h) | Colipase* (U/kg/h) | Total lipase* (U/kg/h) |
Values are mean (SD). | |||||||
CFTR, cystic fibrosis transmembrane regulator. | |||||||
*p<0.0001 for Kruskal-Wallis, χ2, with 4 df. | |||||||
†p=0.01. | |||||||
‡p=0.001. | |||||||
Class I | 7 | 2.3 (1.5) | 0.03 (0.02) | 0.15 (0.14) | 19 (42) | 142 (201) | 290 (388) |
Class II | 33 | 2.9 (2.4) | 0.04 (0.04) | 0.21 (0.33) | 31 (63) | 111 (197) | 202 (276) |
Class III | 6 | 1.1 (0.87) | 0.02 (0.02) | 0.12 (0.07) | 109 (256) | 235 (483) | 608 (1280) |
Class IV | 14 | 4.0 (2.8) | 0.19 (0.2) | 0.32 (0.12) | 1032 (768) | 9840 (10698) | 12563 (10461) |
Class V | 10 | 4.8 (3.2) | 0.12 (0.07) | 0.36 (0.23) | 1535 (1406) | 12161 (13550) | 16449 (15482) |
Control | 21 | 10.0 (3.9) | 0.57 (0.22) | 0.62 (0.3) | 2291 (836) | 13036 (5958) | 19767 (8623) |