Effect of intraperitoneal monodose of 120 mg/kg tazobactam-piperacillin (TZP) and 1 mg/kg IB-367 on mortality in sham operated rats and bile duct ligated (BDL) rats
| Time (h) | Sham placebo | Sham TZP | Sham IB-367 | BDL placebo | BDL TZP | BDL IB-367 |
|---|---|---|---|---|---|---|
| 0 | 1 | 1 | 1 | 1 | 1 | 1 |
| 6 | 1 | 1 | 1 | 0.65 | 0.75 | 0.9 |
| 12 | 1 | 1 | 1 | 0.5 | 0.65 | 0.9 |
| 24 | 1 | 1 | 1 | 0.35 | 0.5 | 0.9 |
| 36 | 1 | 1 | 1 | 0.3 | 0.45 | 0.9 |
| 48 | 1 | 1 | 1 | 0.3 | 0.45 | 0.9 |