Age (y) | 63.9 | 62.1 | 59.8 |
Male (%) | 29.2 | 31.9 | 38.3 |
Moderate or heavy drinker (%) | 0.8 | 1.1 | 3.2 |
Moderate or heavy smoker (%) | 1.1 | 2.4 | 6.8 |
Recent endoscopy (%) | 0.1 | 0.2 | 0.0 |
Recently diagnosed gastric event (%) | 1.8 | 1.2 | 0.6 |
History of H2 antagonist use (%) | 42.4 | 34.9 | 14.6 |
History of PPI use (%) | 35.9 | 23.5 | 4.9 |
History of misoprostol use (%) | 3.4 | 3.3 | 1.9 |
Recently diagnosed dyspepsia (%) | 0.3 | 0.2 | 0.1 |
Recent use of antacids (%) | 6.9 | 5.6 | 3.9 |
Recent use of UHDs (%) | 23.4 | 19.4 | 8.1 |
% of prior 6 months exposed to UHDs | 2.1 | 2.3 | 1.9 |
Any history of dyspepsia (%) | 17.5 | 12.7 | 6.1 |
Any history of gastrointestinal events (%) | 35.2 | 25.8 | 11.7 |
Recent use of local anaesthetics (%) | 6.9 | 5.6 | 3.9 |
OA patients (%) | 34.3 | 30.5 | 19.8 |
Recently diagnosed OA (%) | 9.5 | 5.8 | 2.5 |
RA patients (%) | 10.4 | 11.7 | 7.1 |
Recently diagnosed RA (%) | 2.1 | 2.3 | 0.9 |
Exposure initiated after recent back pain (%) | 4.0 | 5.7 | 5.1 |
Exposure initiated after a recent sprain or strain (%) | 0.6 | 0.6 | 1.3 |
Repeat NSAID users (%) | 93.5 | 92.6 | 81.0 |
% of prior 6 months exposed to NSAIDs | 2.1 | 2.3 | 1.9 |
No of GP contacts in prior 6 months | 1.8 | 1.6 | 1.1 |
Recent use of nitrates and CCBs (%) | 12.4 | 11.8 | 9.1 |
Recent use of corticosteroids (%) | 4.6 | 4.8 | 2.5 |
Recent use of anticoagulants (%) | 0.7 | 0.4 | 0.3 |