Standardised incidence ratios (SIRs) and 95% confidence intervals (CIs) for squamous cell carcinoma of the oesophagus among pernicious anaemia patients, stratified by follow up duration and age at index hospitalisation
| Total | Without alcohol related diseases† | |||||
|---|---|---|---|---|---|---|
| Characteristic | Obs* | SIR | 95% CI | Obs* | SIR | 95% CI |
| *Observed number of cancer cases | ||||||
| †Person years before the onset of comorbid diseases were allocated to the comorbidity negative stratum. | ||||||
| Follow up (y) | ||||||
| 1–4 | 14 | 2.2 | 1.2–3.7 | 14 | 2.3 | 1.3–3.9 |
| 5–9 | 15 | 3.8 | 2.1–6.3 | 13 | 3.5 | 1.8–5.9 |
| ⩾10 | 14 | 4.9 | 2.7–8.2 | 14 | 5.1 | 2.8–8.6 |
| p value for trend | 0.03 | 0.03 | ||||
| Age at index hospitalisation | ||||||
| <50 | 3 | 10.4 | 2.2–30.4 | 3 | 11.3 | 2.3–33.0 |
| 50–69 | 20 | 4.4 | 2.7–6.9 | 18 | 4.3 | 2.6–6.8 |
| ⩾70 | 20 | 2.4 | 1.5–3.7 | 20 | 2.5 | 1.5–3.8 |
| p value for trend | 0.01 | 0.01 | ||||