Body weight, liver weight, and plasma parameters of lean and obese Zucker rats
| 8 week old ZR | 14 week old ZR | |||
|---|---|---|---|---|
| Lean (?/fa) | Obese (fa/fa) | Lean (?/fa) | Obese (fa/fa) | |
| Data represent mean (SD), n = 3–12 per group. | ||||
| ZR, Zucker rat; AST, aspartate aminotransferase; ALT, alanine aminotransferase. | ||||
| *p<0.05 compared with respective lean control. | ||||
| Body weight (g) | 198 (7.4) | 251.2 (7.9)* | 263.4 (21.7) | 411.0 (17.4)* |
| Liver weight (g) | 6.2 (0.21) | 9.4 (0.36)* | 7.1 (0.4) | 12.8 (0.9)* |
| Body/liver weight | 32.1 (0.7) | 26.8 (0.76)* | 36.6 (1.3) | 33.0 (1.9) |
| Glucose (mg/dl) | 132.9 (6.5) | 151.2 (9.1)* | 119.6 (2.9) | 191.9 (12.6)* |
| AST (U/l) | 84.8 (4.3) | 193.4 (19.4)* | 110.5 (5.8) | 147.7 (13.5) |
| ALT (U/l) | 46.9 (4.9) | 58.0 (0.2) | 67.8 (6.1) | 66.6 (5.0) |
| Cholesterol (mg/dl) | 72.1 (2.6) | 123.9 (32.2)* | 74.1 (8.0) | 96.0 (8.8) |
| Triglycerides (mg/dl) | 33.7 (2.9) | 293.8 (59)* | 40.4 (7.1) | 418.2 (68.7)* |
| Bilirubin (µmol/l) | 9.0 (1.0) | 10.9 (1.3) | 4.4 (0.23) | 4.4 (1.4) |