Systemic and splanchnic haemodynamics in the two study groups
| No PPHTN | PPHTN | |
|---|---|---|
| Values are mean (SEM). | ||
| PPHTN, portopulmonary hypertension; CO, cardiac output; SVR, systemic vascular resistance; mRAP, mean right atrial pressure; mRVP, mean right ventricular pressure; IVC, inferior vena cava. | ||
| ***p<0.001, PPHTN versus no PPHTN. | ||
| n=52 for the no PPHTN group and n=10 for the PPHTN group unless otherwise stated | ||
| CO (ml/min) (normal 4150–6575) | 4768 (391) (n=39) | 4057 (492) (n=10) |
| SVR (dyn×s/cm5) (normal 700–1600) | 1795 (145) (n=39) | 2075 (259) (n=10) |
| mRAP (mm Hg) (normal ≤7) | 7.9 (0.5) | 15.4 (1.2)*** |
| mRVP (mm Hg) (normal ≤15) | 14.7 (0.6) | 24.7 (4.7)*** |
| IVC pressure (mm Hg) (normal ≤6) | 14.6 (0.7) | 18.8 (1.8) |
| Free hepatic venous pressure (mm Hg) (normal ≤5) | 13.7 (0.7) | 17.4 (1.3) |
| Wedged hepatic venous pressure (mm Hg) (normal ≤15) | 31.6 (1.0) | 35.2 (2.5) |
| Portal pressure (mm Hg) (normal ≤15) | 33.8 (1.2) | 34.7 (1.8) |
| Corrected sinusoidal pressure (mm Hg) (normal ≤7) | 18.0 (0.7) | 17.8 (1.2) |