Reasons for premature discontinuation of the study
| Reason for premature discontinuation* | EcN (n = 162) | Mesalazine (n = 165) |
|---|---|---|
| *Multiple reasons possible. | ||
| EcN, Escherichia coli Nissle 1917. | ||
| Deterioration of disease (relapse not included) | 1 (0.6%) | 1 (0.6%) |
| Newly emerged exclusion criterion during study | 4 (2.5%) | 2 (1.2%) |
| Patient’s request | 13 (8.0%) | 9 (5.5%) |
| Adverse events | 3 (1.9%) | 6 (3.6%) |
| Insufficient patient compliance | 6 (3.7%) | 6 (3.6%) |
| Insufficient patient cooperation (diary) | 6 (3.7%) | 3 (1.8%) |
| Patient did not appear anymore | 2 (1.2%) | 5 (3.0%) |
| Other reasons | 1 (0.6%) | 2 (1.2%) |
| Patients with premature discontinuation | 19 (11.7%) | 20 (12.1%) |