Agonists
| 8-OH-DPAT | Sumatriptan | α-Me-5-HT | α-Me-5-HT | 2-Me-5-HT | Tegaserod | 5-CT 8-OH | Hydroxylated indalpines |
| Buspirone | Rizatriptan | | BW723C86 | CPBG | Prucalopride | DPAT | |
| | Naratriptan | | | | | | |
Antagonists
| WAY100635 | GR127935 (5-HT1B/D antagonist) | Ketanserin, | SB200646 | Ondansetron | GR113808 | Methiotepin | 5-HTP-DP |
| | SB216641 (5-HT1B-selective) | MDL100907 | SB204741 | Alosetron | GR125487 | Metergoline | |
| | BRL15572 (5-HT1D–selective) | | | Cilansetron | Piboserod | SB258719 | |
| | | | | | | SB269970 | |
| | | | | | | SB656104 | |
Effectors
| Gi/o | Gi/o | Gq/11 | Gq/11 | Ligand gated ion channel | Gs | Gs | Go |
Distribution in the gut
| Enteric neurones | Enteric neurones (?) | Smooth muscle | Longitudinal smooth muscle | Enteric neurones | Enteric neurones, smooth muscle, enterocytes | Smooth muscle, enteric neurones (?) | Enteric neurones |
| | Circular smooth muscle (?) | | | | | | |
Functional response on stimulation
| ↓Transmitter release | Gastric relaxation | Contraction | Contraction | fEPSP, ↑ transmitter release, ↑secretion | ↑Transmitter release, relaxation, ↑ secretion | Relaxation | Slow EPSP |