Subject characteristics (mean (SEM))
| d-IBS patients (n = 14) | Controls (n = 14) | Patients v controls (p value†) | |
|---|---|---|---|
| d-IBS, diarrhoea-predominant IBS; MINI, mini international neuropsychiatric interview; HAM-D17, 17 item Hamilton depression rating scale; SCL-90, symptom checklist; GSI, global severity index; HADS, hospital anxiety and depression rating scale. | |||
| *Significant difference between groups. | |||
| †Independent samples t tests comparing d-IBS patients versus control subjects. | |||
| ‡Four subjects had a psychiatric diagnosis: depression, agoraphobia, social phobia, and anxiety disorder, respectively. | |||
| Sex (F/M) (n) | 8/6 | 8/6 | – |
| Oral contraceptives (n) | 6/8 | 6/8 | – |
| Age | 34.1 (3.0) | 33.9 (3.8) | 0.7 |
| Intelligence quotient | 106 (3.6) | 110 (3.0) | 0.5 |
| Body mass index | 23.3 (1.0) | 22.9 (0.7) | 0.7 |
| Alcohol units/day | 0.61 (0.2) | 0.52 (0.1) | 0.8 |
| Cigarettes/day | 2.71 (1.2) | 1.43 (0.9) | 0.2 |
| Diagnosis on MINI | 4‡ | 0 | – |
| HAM-D17 | 3.64 (1.1) | 0.86 (0.3) | 0.03* |
| SCL-90 (GSI) | 114 (6.3) | 97.4 (2.3) | 0.02* |
| HADS (total) | 5.14 (0.9) | 3.93 (0.9) | 0.34 |