Antimicrobial therapy of persistent infectious diarrhoea
| Enteropathogen | Antimicrobial therapy | Alternative(s) |
|---|---|---|
| The treatment of other bacterial infections that can cause persistent diarrhoea (see table 1) can be found in table 5(references). | ||
| Protozoa | ||
| Giardia intestinalis | Metronidazole 400 mg tds 7–10 days80 | Tinidazole 2 g single dose80 |
| Cryptosporidium parvum | ?Paromomycin 500 mg qds71 | ?Nitazoxanide14 |
| Cyclospora cayetanensis | TMP-SMX 2 tabs bd 7 days79 | |
| Isospora belli | TMP-SMX 2 tabs qds 10 days | |
| Microsporidia | ||
| Encephalitozoon intestinalis | ? Albendazole 400 mg bd 14–28 days73 | ?Furazolidone 100 mg qds 20 days76 |
| Enterocytozoon bieneusi | ? Atovaquone75 | |
| Entamoeba histolytica | See table 5 | |
| Balantidium coli | See table 5 | |
| Helminths | ||
| Strongyloides stercoralis | Albendazole 400 mg od 3 days | Thiabendazole 25 mg/kg bd 2–3 days |
| Schistosoma spp | Praziquantel 2–3 doses on day 1 | Ivermectin 100–200 μg/kg od 2 days |
| S mansoni, S haematobium | Praziquantel 40 mg/kg/d | |
| S japonicum | Praziquantel 60 mg/kg/d | |
| Virus | ||
| Cytomegalovirus | Ganciclovir 5 mg/kg bd 14–21 days | Foscarnet 60 mg/kg tds 14–21 days maintenance therapy required |